Sealing of a device with nanofluidic channels
To detect DNA by means of its stretching in nanochannels.
Sealing of a device with nanofluidic channels.
Current methods of DNA analysis require cutting up each molecule into millions of fragments, replicating each segment, classifying them by size and reconstructing the original strands of DNA using costly and lengthy processes.
The processes for stretching strands of DNA, involving in aligning the DNA molecules by confinement in nanofluidic channels, open new possibilities for the analysis of DNA and the biochemical sensor system, enabling the acceleration of these processes and reducing their costs.
In order to obtain these devices (and others which include nanochannels, as well as devices for the separation of charged analytes), it is necessary to employ robust bonding processes which use reduced force to avoid the collapse of the channels.